Title

The Effects of Drug-Induced Alterations of the Autonomic Nervous System on the Responses of Mammals to Oxygen Deprivation

Date

1952

Index Abstract

Coming Soon

Photo Quality

Undetermined

Report Number

WADC TR 52-222

Creator

Bauer, Robert O.

Dustin, Eben H.

Maison, George L.

Stutzman, Jacob W.

Gourzis, James T.

Corporate Author

Boston University

Extent

57

Identifier

ADA075876

Access Rights

Unknown

Distribution Classification

1

DTIC Record Exists

Yes

Distribution Change Authority Correspondence

None

Abstract

The cardiovascular reactions of the mammal to sudden withdrawal of oxygen from the inspired atmosphere include rise of blood pressure and rise of heart rate. While reflexes activating the sympathetic division of the autonomic nervous system are involved in creating these responses, the importance of epinephrine release and of neural activation of arterial musculature in specific areas remain unassessed. With the discovery in recent years of new chemical agents which present with varying specificity abilities to block the autonomic effector paths, the possibility beckons that use of these drugs may elicit basic information about the reaction to oxygen want. Accordingly several hundred experiments were performed in anesthetized dogs and rabbits. Clarification of the mechanisms did not result but certain items of basic information gleaned have been reproduced here in the form of their scientific publication.

Report Availability

Not available via Contrails

Date Issued

1952-06

Index In

DTIC

Type

report