Evaluation of Immunoassay Methods for Prolactin in Body Fluids

Item

Title
Evaluation of Immunoassay Methods for Prolactin in Body Fluids
Date
1966
Index Abstract
Not Available
Photo Quality
Complete
Report Number
AMRL TR 66-113
Creator
Dilley, D. A.
Corporate Author
Aerospace Medical Research Laboratories
Laboratory
Aerospace Medical Research Laboratories
Extent
32
Identifier
AD0646432
Access Rights
Distribution of this document is unlimited
Distribution Classification
1
Contract
Laboratory Research - No Contract
DoD Project
6302
DoD Task
630202
DTIC Record Exists
Yes
Distribution Change Authority Correspondence
None
Distribution Conflict
No
Abstract
A practical immunologic assay to detect the hormone, prolactin, in body fluids was evaluated. Prolactin content was assayed using positive antiprolactin sera prepared in rabbits and test samples of serum, urine, and urinary extract from a borane exposed female monkey in micro-Ouchterlony gel diffusion and agglutination inhibition tests. The gel diffusion test gave qualitative results while the agglutination inhibition test allowed quantitation of prolactin content. Results of the later test indicated a possible difference in pre- and postborane exposure prolactin content of monkey urine. Further work in this area will need to be done to clarify this preliminary evidence and to expand on its applicability to human exposure to boranes.
Report Availability
Full text available
Date Issued
1966-09
Provenance
RAF Centre of Aviation Medicine
Type
report
Format
1 online resource