Title

Models of Neuroelectric Interactions

Date

1967

Index Abstract

Not Available

Photo Quality

Complete

Report Number

AMRL TR 67-132

Corporate Author

Librascope Group, General Precision Systems, Inc.

Laboratory

Aerospace Medical Research Laboratories

Extent

148

Identifier

AD0669574

AD0669574

Access Rights

CFSTI

Distribution Classification

1

Contract

AF 33(615)-2464

DoD Project

7233 - Biological Information Handling Systems and Their Functional Analogs

DoD Task

723305 - Theory of Information Handling

DTIC Record Exists

No

Distribution Change Authority Correspondence

None

Distribution Conflict

No

Abstract

The Hodgkin-Huxley descriptions of electrically excitable conductances are combined with Eccles descriptions of synaptic conductances to provide the basis of an electronic analog of nerve cell membrane. A neural simulation facility is constructed, comprising ten pairs of these analogs with associated input and output equipment. A detailed description of the simulation facility is presented, including design philosophy, circuit, system and mechanical details. The simulation facility is used to model spatially distributed neuroelectric phenomena. Significant results include resetting of potentials in integrative regions by spikes generated at a remote site, stable spike synchrony in independently driven, mutually inhibiting distributed neural models, burst formation in mutually exciting neural models, and various nonuniformities of wave shape and velocity in conduction along a distributed axon. In addition, the facility is used in a simulation study of the lobster cardiac ganglion. As results of this study, mechanisms are proposed for ganglion operation and specific neuronal connectivities are predicted.

Report Availability

Full text available

Date Issued

1967-12

Provenance

RAF Centre of Aviation Medicine

Type

report

Format

1 online resource

Subject

Nervous System

Bionics

Nerve Cells

Electrophysiology

Nerve Impulses

Ganglia

Mathematical Models

Analog Systems

Circuits

Electrolytes (Physiology)

Inhibition

Crustacea

Electrical Conductivity

Interactions

Creator

Lewis, Edwin R.